Titans at Colts betting preview: Indianapolis looks to take control of AFC South over Tennessee

Indianapolis Colts running back Jonathan Taylor (28) runs to the outside during an NFL football game against the Kansas City Chiefs, Sunday, Sept. 25, 2022, in Indianapolis. (AP Photo/Zach Bolinger)

BY COREY LONG | Home Field Sports

The Indianapolis Colts and Tennessee Titans will renew their AFC South rivalry Sunday afternoon at Lucas Oil Stadium.


Both teams earned their first wins of the season last week. Indianapolis (1-2) defeated the Kansas City Chiefs 20-17 after quarterback Matt Ryan threw a 12-yard touchdown pass to Jelani Woods with 24 seconds remaining.


Tennessee (1-2) stormed out to a 24-10 halftime lead against the Las Vegas Raiders but needed to defend a late 2-point conversion to hold on for a 24-22 win. Ryan Tannehill threw for 264 yards and a touchdown. He also rushed for a score.


Caesars Sportsbook has listed the Colts as a 3.5-point favorite with an over/under of 42


Let’s take a closer look at the odds and trends:


Tennessee Titans at Indianapolis Colts


Time/TV: 1 p.m. ET Sunday, Fox


Point spread (from Caesars Sportsbook): Colts -3.5


Money line: Titans +150; Colts -179


Over/under: 42.5


Analysis: The Football Power Index, an ESPN analytics system, gives Indianapolis a 60.4% chance to win Sunday. The Colts have one of the best rush defenses in the league, and they will have a very tough challenge in Titans running back Derrick Henry.  Henry appears to be warming up after a slow start to the season. He had 20 carries for 85 yards and a touchdown against the Raiders last week.


The Colts should hope that quarterback Matt Ryan will be able to build on a solid game against the Chiefs when he was 27-of-37 passing for 222 yards and two touchdowns. Running back Jonathan Taylor missed practice early in the week recovering from a toe injury. He is expected to play Sunday, but Taylor has never rushed for more than 70 yards against the Titans.


Expect this to be a back-and-forth battle as neither team wants to get behind too far in the division. The Colts win with a late field goal.


Prediction: Colts 27, Titans 24



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